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Systematic Reviews

A type of literature review that uses a systematic and rigorous approach to identify, select, appraise, and synthesize all available evidence on a particular topic.

Further information

There are several sites with systematic review databases.  Many of these are indexed in Medline/PubMed.  If you have not checked there first, do so!  Search these sites to make sure, especially PROSPERO as it is a registry of SR protocols.

Centre for Reviews & Dissemination (University of York)

  • PROSPERO: Registry of systematic review protocols.
  • Search CRD Database : This organization produces DARE (Database of Abstracts of Reviews of Effects) and provides content to the Cochrane Library. A search at this site (updated daily) draws evidence-based healthcare information from DARE, the National Health Service's Economic Evaluation Database (EED), and the Health Technology Assessment (HTA) database. CRD provides systematic reviews, economic evaluations and health technology assessments on your topic of interest. 

ClinicalTrials.govRegisters trials that are recruiting and reports which have been completed.  It also has results for many studies.  Since a majority of the trials in this registry are never published, you'll need to search here if you're looking or clinical trial data.

WHO International Clinical Trials Registry Platform: This is a meta-site; multiple national registries meet the standards established by the WHO ICTRP (including ClinicalTrials.gov).  

Agency for Health Research & Quality

EPPI-Center